Compare Treatments · Depth, Pain & Genuine Machine Check
Profhilo vs. Skinvive / Belotero Revive
5-point BAP deep-dermal HA vs. superficial micro-droplet HA + glycerol hydration. Both lit on one cross-section — A solid, B dashed — with every layer either reaches outlined.
Depth chartSkin Depth Chart (Tap to Zoom) ↓ Download WebP
Side-by-Side Treatment Comparison
1 · How It Works & Maker
Intradermal PN / BAP Hybrid HA
IBSA Derma (Switzerland)
Microdroplet Intradermal HA (+ Glycerol)
AbbVie (Allergan) · Merz
2 · Skin Layers & Exact Depth
2.5–3.5mm
- Reticular Dermis (1.5–3.0mm)
- Subcutaneous Fat (3.0–4.2mm)
0.8–1.2mm
- Papillary Dermis (0.3–1.5mm)
3 · Pain Level & Numbing
3/10
Usually none — only 10 injection points.
4/10
Topical numbing 20–30 minutes (Skinvive also contains lidocaine).
4 · Recovery Time & Repeat Schedule
24–48 hrs small injection bumps
Repeat: 2 sessions 4 weeks apart, then every 6 months
24–48 hrs small bumps / redness
Repeat: Every 6 months
5 · Singapore 2026 Fair Price (incl. GST)
S$780–S$1,150
Typical median: S$950 · Per 2ml syringe (5-point BAP technique per side)
Check My Quote →S$820–S$1,180
Typical median: S$980 · Per 2ml treatment (2 × 1ml syringes, 1ml per cheek)
Check My Quote →6 · How to Spot a Fake / Clone Machine
Each authentic box carries a scannable QR / lot code from the authorised Singapore distributor (NeoAsia). Ask the doctor to scan it with you before opening.
- ✓Box QR code scanned in front of you
- ✓IBSA lot number and expiry match
- ✓Syringe unopened until the procedure starts
Check the syringe brand, lot and expiry, and that it is opened in front of you. Ask whether the quote covers 1ml or the usual 2ml.
- ✓Sealed syringe opened in front of you
- ✓Lot & expiry match the box
- ✓2ml quoted for both cheeks
Goes deeper: Profhilo (Subcutaneous Fat)
Less painful: Profhilo (3/10 vs 4/10)
Lower median per session: Profhilo (S$950 vs S$980)
IBSA Profhilo · Profhilo Structura
Profhilo
Thermally stabilised hybrid cooperative HA complex (32mg H-HA + 32mg L-HA) diffuses from 5 Bio Aesthetic Points per side for bio-remodelling.
IndicationsSkin laxity, crepiness, hydration, neck and décolletage
Audit a Profhilo quote · SG median S$950 →- Energy / Modality
- Intradermal PN / BAP Hybrid HA
- Target Anatomical Layer
- Reticular Dermis 1.5–3.0mm
Subcutaneous Fat 3.0–4.2mm - Clinical Pain Index
- 3/10
- Usually none — only 10 injection points.
- Social Downtime
- 24–48 hrs small injection bumps
- Evidence-Based Interval
- 2 sessions 4 weeks apart, then every 6 months
Counterfeit / Clone Machine Warning
Each authentic box carries a scannable QR / lot code from the authorised Singapore distributor (NeoAsia). Ask the doctor to scan it with you before opening.
- ✓Box QR code scanned in front of you
- ✓IBSA lot number and expiry match
- ✓Syringe unopened until the procedure starts
- Halley Medical Aesthetics
Orchard Road · Tier A
- Bio Aesthetic Laser Clinic (Palais Renaissance)
Orchard Road · Tier B
Comparison Matrix
| Device | Energy / Modality | Target Layer | Pain | Downtime | Interval | SG Median |
|---|---|---|---|---|---|---|
| Pico Laser Quanta · Candela · Cynosure · Fotona |
1064nm/532nm Picosecond Nd:YAG | Epidermis 0.1–0.3mm (532nm) · Papillary Dermis 0.3–1.5mm (1064nm / MLA) | 2/10 | 0 hrs (toning) · 24–48 hrs erythema (fractional) | Every 2–4 weeks × 5–10 (toning) · every 4 weeks × 3–4 (fractional) | S$350 |
| Sylfirm X Viol Co., Ltd. (Korea) |
300μm–4.0mm Bipolar Pulsed/CW RF | Basement Membrane 0.3mm (PW) · Papillary & Reticular Dermis to 3.0mm+ (CW) | 5/10 | 24–48 hrs erythema · pinpoint marks 2–3 days | Every 4 weeks × 3–5 | S$680 |
| Thermage FLX Solta Medical (Bausch Health) |
6.78 MHz Monopolar RF | Reticular Dermis 1.5–3.0mm · Fibrous Septae to ~4.0mm | 6/10 | 0–24 hrs mild erythema | Annual single session (12–18 months) | S$3,500 |
| Ultherapy PRIME Merz Aesthetics |
MHz Micro-Focused Ultrasound + Real-Time Ultrasound Imaging | 1.5mm Dermis · 3.0mm Deep Dermis · 4.5mm SMAS Fibromuscular Layer | 8/10 | 0 hrs social downtime · tenderness 1–2 weeks | Annual single session (12–18 months) | S$3,200 |
| Sofwave Sofwave Medical |
SUPERB Synchronous Ultrasound Parallel Beam | Mid-Dermis Parallel Cylinder Zone 1.5mm (spares SMAS & subcutaneous fat) | 6/10 | 0–24 hrs mild redness | Annual single session (optional 6-month top-up) | S$3,200 |
| Potenza Cynosure |
4-Mode Monopolar/Bipolar RF Microneedling | 0.5mm–4.0mm Dual-Depth (Tiger Tip treats two dermal depths per pass) | 6/10 | 24–72 hrs erythema · pinpoint marks | Every 4–6 weeks × 3 | S$850 |
| Fotona 4D Fotona |
2940nm Er:YAG + 1064nm Nd:YAG (4 modes) | 0.1mm Epidermal Peel · 1.0–3.0mm Bulk Dermal Heating · Intraoral Mucosal Vector | 4/10 | 0–24 hrs (SupErficial: 2–3 days fine peeling) | Every 4–6 weeks × 3, then every 6 months | S$750 |
| Rejuran Healer PharmaResearch (Korea) |
Intradermal PN (Polynucleotide 2%) | Papillary Dermis 0.5–1.5mm (intradermal blebs) | 7/10 | 3–5 days micro-bumps / subdermal papules (gun) · 1–2 days (manual) | Every 3–4 weeks × 3, then maintenance every 6 months | S$650 |
| Profhilo IBSA Derma (Switzerland) |
Intradermal PN / BAP Hybrid HA | Deep Dermis / Superficial Subcutaneous ~2.5–3.5mm (BAP depots) | 3/10 | 24–48 hrs small injection bumps | 2 sessions 4 weeks apart, then every 6 months | S$950 |
| Botulinum Toxin Merz · AbbVie (Allergan) · Ipsen / Galderma |
Botulinum Toxin Type A Neuromodulator | Intramuscular (Masseter / Frontalis / Corrugator >4.5mm) · Intradermal Micro-Botox (0.8–1.2mm) | 3/10 | 0 hrs · pinpoint bumps for 15–30 minutes | Every 3–4 months (masseter 4–6 months) | S$650 |
| Juvelook / Lenisna Vaim Co. (Korea) |
PDLLA + Non-Crosslinked HA Biostimulator | Papillary to Reticular Dermis 1.0–1.8mm (Juvelook 50mg) · Subdermal 2.5–4.0mm (Lenisna 200mg) | 5/10 | 1–3 days micro-papules | Every 4–6 weeks × 2–3, then yearly | S$780 |
| Skinvive / Belotero Revive AbbVie (Allergan) · Merz |
Microdroplet Intradermal HA (+ Glycerol) | Superficial Intradermal Microdroplet Depot 0.8–1.2mm | 4/10 | 24–48 hrs small bumps / redness | Every 6 months | S$980 |
Pillar II · Singapore 2026 Fair Price
Audit Both Quotes
Protocol A · Per 2ml syringe (5-point BAP technique per side)
Profhilo
Fair S$780–S$1,150 · median S$950
Profhilo under ~S$650 per syringe warrants checking the box QR code and lot number in front of you.
Audit Your Profhilo Quote →Protocol B · Per 2ml treatment (2 × 1ml syringes, 1ml per cheek)
Skinvive / Belotero Revive
Fair S$820–S$1,180 · median S$980
Under ~S$680 for 2ml often means a single 1ml syringe spread across both cheeks.
Audit Your Skinvive Quote →SGD incl. 9% GST · medians are per each treatment's own reference dose, so compare them as typical courses, not like-for-like units · editorial benchmarks, not clinic tariffs.
Clinic Dossier · Singapore
Matched Singapore Clinics
Profhilo
- Halley Medical Aesthetics
Orchard Road · Tier A
- Bio Aesthetic Laser Clinic (Palais Renaissance)
Orchard Road · Tier B
Skinvive / Belotero Revive · no listed tariff yet — most transparent practices
- Halley Medical Aesthetics
Orchard Road · Tier A
- V Medical Aesthetics & Laser Clinic (Somerset)
Somerset / Orchard · Tier A
- Bio Aesthetic Laser Clinic (Palais Renaissance)
Orchard Road · Tier B
Clinic Dossier · Listed
Listed in Our Clinic Directory
Bio Aesthetic Laser Clinic (Palais Renaissance) is the one clinic in the dossier that lists Profhilo or Skinvive / Belotero Revive. Compare it with its closest medical aesthetic clinic peers.
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Bio Aesthetic Laser Clinic (Palais Renaissance)
Singapore · Medical Aesthetic Clinic
Orchard Exit 11 · 292 mTier BLists: Fotona StarWalker MaQX Pico Laser · HydraFacial · Profhilo / Skin Boosters
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Halley Medical Aesthetics
Singapore · Medical Aesthetic Clinic
Somerset Exit D · 54 mTier APeer for comparison
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V Medical Aesthetics & Laser Clinic (Somerset)
Singapore · Medical Aesthetic Clinic
Somerset Exit A · 120 mTier APeer for comparison
Section V · Before Profhilo or Skinvive / Belotero Revive
Pre-Procedure Washout & Post-Procedure Barrier Support
Injectables usually need no washout beforehand, but keep exfoliating acids, retinoids and spicule products off the injected area for 24–48 hours after.
Compare audited examples: retinoid, exfoliating acid, spicule →After the session · Recovery & photoprotection
- Cicaplast Baume B5+ Soothing Therapeutic CreamLa Roche-Posay · Barrier / Peptide / Hydrator
- Atobarrier 365 CreamAestura · Barrier / Peptide / Hydrator
- Madagascar Centella Hyalu-Cica Water-Fit Sun Serum SPF50+ PA++++SKIN1004 · Photoprotection
Editorial guidance from common clinic practice, not medical advice: your treating doctor's pre- and post-care instructions come first.
How It Works
RF Microneedling & Intradermal Boosters
Field Notes
Frequently Asked Questions
What is the difference in skin depth and mechanism between Profhilo and Skinvive / Belotero Revive?
Profhilo (Intradermal PN / BAP Hybrid HA) works at Deep Dermis / Superficial Subcutaneous ~2.5–3.5mm (BAP depots) — Reticular Dermis (1.5–3.0mm), Subcutaneous Fat (3.0–4.2mm). Thermally stabilised hybrid cooperative HA complex (32mg H-HA + 32mg L-HA) diffuses from 5 Bio Aesthetic Points per side for bio-remodelling. Skinvive / Belotero Revive (Microdroplet Intradermal HA (+ Glycerol)) works at Superficial Intradermal Microdroplet Depot 0.8–1.2mm — Papillary Dermis (0.3–1.5mm). Lightly cross-linked HA (Belotero Revive adds glycerol) placed as superficial intradermal microdroplets for hydration and glow rather than volume. Profhilo reaches the deeper layer (Subcutaneous Fat).
Which is more painful or has longer downtime: Profhilo or Skinvive / Belotero Revive?
Profhilo: pain 3/10 — Usually none — only 10 injection points. Downtime 24–48 hrs small injection bumps; interval 2 sessions 4 weeks apart, then every 6 months. Skinvive / Belotero Revive: pain 4/10 — Topical numbing 20–30 minutes (Skinvive also contains lidocaine). Downtime 24–48 hrs small bumps / redness; interval Every 6 months. Profhilo is the gentler of the two on Beauty.net's clinical pain index.
How much does Profhilo vs. Skinvive / Belotero Revive cost in Singapore in 2026 and which should I choose?
Beauty.net's 2026 Singapore benchmarks (SGD incl. 9% GST, editorial percentiles rather than clinic tariffs): Profhilo S$780–S$1,150, median S$950 (Per 2ml syringe (5-point BAP technique per side)); Skinvive / Belotero Revive S$820–S$1,180, median S$980 (Per 2ml treatment (2 × 1ml syringes, 1ml per cheek)). Choose by indication rather than price — Profhilo: Skin laxity, crepiness, hydration, neck and décolletage; Skinvive / Belotero Revive: Dehydrated skin, fine cheek lines, dullness. A doctor's assessment of your skin decides which layer needs treating.