Compare Treatments · Depth, Pain & Genuine Machine Check
Botulinum Toxin Depth & Authenticity — IM >4.5mm
Botulinum Toxin works at Intramuscular (Masseter / Frontalis / Corrugator >4.5mm) · Intradermal Micro-Botox (0.8–1.2mm). Pick any protocol below, or compare two head-to-head on the same cross-section.
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Xeomin · Botox · Dysport
Botulinum Toxin
Blocks acetylcholine release at the neuromuscular junction — intramuscular for masseter and frown muscles, intradermal micro-dosing for pores and oil.
IndicationsMasseter hypertrophy / jaw slimming, forehead and frown lines, crow's feet, micro-Botox for pores and oil
Audit a Botulinum Toxin quote · SG median S$650 →- Energy / Modality
- Botulinum Toxin Type A Neuromodulator
- Target Anatomical Layer
- Papillary Dermis 0.3–1.5mm
SMAS Fibromuscular Layer Fibromuscular · 4.5mm - Clinical Pain Index
- 3/10
- Usually none; ice or topical numbing for micro-Botox.
- Social Downtime
- 0 hrs · pinpoint bumps for 15–30 minutes
- Evidence-Based Interval
- Every 3–4 months (masseter 4–6 months)
Counterfeit / Clone Machine Warning
Ask to see the brand, lot and expiry on the vial and the dilution volume. Grey-market and counterfeit toxin vials circulate online; Singapore clinics should only use HSA-registered product. Dysport units are not interchangeable with Botox or Xeomin units.
- ✓HSA-registered brand, lot and expiry on the vial
- ✓Dilution volume stated
- ✓Units recorded in your notes
- Halley Medical Aesthetics
Orchard Road · Tier A
Comparison Matrix
| Device | Energy / Modality | Target Layer | Pain | Downtime | Interval | SG Median |
|---|---|---|---|---|---|---|
| Pico Laser Quanta · Candela · Cynosure · Fotona |
1064nm/532nm Picosecond Nd:YAG | Epidermis 0.1–0.3mm (532nm) · Papillary Dermis 0.3–1.5mm (1064nm / MLA) | 2/10 | 0 hrs (toning) · 24–48 hrs erythema (fractional) | Every 2–4 weeks × 5–10 (toning) · every 4 weeks × 3–4 (fractional) | S$350 |
| Sylfirm X Viol Co., Ltd. (Korea) |
300μm–4.0mm Bipolar Pulsed/CW RF | Basement Membrane 0.3mm (PW) · Papillary & Reticular Dermis to 3.0mm+ (CW) | 5/10 | 24–48 hrs erythema · pinpoint marks 2–3 days | Every 4 weeks × 3–5 | S$680 |
| Thermage FLX Solta Medical (Bausch Health) |
6.78 MHz Monopolar RF | Reticular Dermis 1.5–3.0mm · Fibrous Septae to ~4.0mm | 6/10 | 0–24 hrs mild erythema | Annual single session (12–18 months) | S$3,500 |
| Ultherapy PRIME Merz Aesthetics |
MHz Micro-Focused Ultrasound + Real-Time Ultrasound Imaging | 1.5mm Dermis · 3.0mm Deep Dermis · 4.5mm SMAS Fibromuscular Layer | 8/10 | 0 hrs social downtime · tenderness 1–2 weeks | Annual single session (12–18 months) | S$3,200 |
| Sofwave Sofwave Medical |
SUPERB Synchronous Ultrasound Parallel Beam | Mid-Dermis Parallel Cylinder Zone 1.5mm (spares SMAS & subcutaneous fat) | 6/10 | 0–24 hrs mild redness | Annual single session (optional 6-month top-up) | S$3,200 |
| Potenza Cynosure |
4-Mode Monopolar/Bipolar RF Microneedling | 0.5mm–4.0mm Dual-Depth (Tiger Tip treats two dermal depths per pass) | 6/10 | 24–72 hrs erythema · pinpoint marks | Every 4–6 weeks × 3 | S$850 |
| Fotona 4D Fotona |
2940nm Er:YAG + 1064nm Nd:YAG (4 modes) | 0.1mm Epidermal Peel · 1.0–3.0mm Bulk Dermal Heating · Intraoral Mucosal Vector | 4/10 | 0–24 hrs (SupErficial: 2–3 days fine peeling) | Every 4–6 weeks × 3, then every 6 months | S$750 |
| Rejuran Healer PharmaResearch (Korea) |
Intradermal PN (Polynucleotide 2%) | Papillary Dermis 0.5–1.5mm (intradermal blebs) | 7/10 | 3–5 days micro-bumps / subdermal papules (gun) · 1–2 days (manual) | Every 3–4 weeks × 3, then maintenance every 6 months | S$650 |
| Profhilo IBSA Derma (Switzerland) |
Intradermal PN / BAP Hybrid HA | Deep Dermis / Superficial Subcutaneous ~2.5–3.5mm (BAP depots) | 3/10 | 24–48 hrs small injection bumps | 2 sessions 4 weeks apart, then every 6 months | S$950 |
| Botulinum Toxin Merz · AbbVie (Allergan) · Ipsen / Galderma |
Botulinum Toxin Type A Neuromodulator | Intramuscular (Masseter / Frontalis / Corrugator >4.5mm) · Intradermal Micro-Botox (0.8–1.2mm) | 3/10 | 0 hrs · pinpoint bumps for 15–30 minutes | Every 3–4 months (masseter 4–6 months) | S$650 |
| Juvelook / Lenisna Vaim Co. (Korea) |
PDLLA + Non-Crosslinked HA Biostimulator | Papillary to Reticular Dermis 1.0–1.8mm (Juvelook 50mg) · Subdermal 2.5–4.0mm (Lenisna 200mg) | 5/10 | 1–3 days micro-papules | Every 4–6 weeks × 2–3, then yearly | S$780 |
| Skinvive / Belotero Revive AbbVie (Allergan) · Merz |
Microdroplet Intradermal HA (+ Glycerol) | Superficial Intradermal Microdroplet Depot 0.8–1.2mm | 4/10 | 24–48 hrs small bumps / redness | Every 6 months | S$980 |
Pillar II · Singapore 2026 Fair Price
Botulinum Toxin: fair S$480–S$850, median S$650
50 units (masseter jaw reduction or 3-area upper face) · SGD incl. 9% GST. A 'S$199 jaw Botox' usually buys 15–20 over-diluted units — too few to reduce masseter hypertrophy.
Transparent practices: Halley Medical Aesthetics
Clinic Dossier · Singapore
Compare Singapore Medical Clinics in Our Directory
No clinic in the dossier lists Botulinum Toxin yet. These are Singapore medical clinics in the Open Directory: compare their doctors, devices and published prices side by side.
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Halley Medical Aesthetics
Singapore · Medical Aesthetic Clinic
Somerset Exit D · 54 mTier A -
V Medical Aesthetics & Laser Clinic (Somerset)
Singapore · Medical Aesthetic Clinic
Somerset Exit A · 120 mTier A -
Bio Aesthetic Laser Clinic (Palais Renaissance)
Singapore · Medical Aesthetic Clinic
Orchard Exit 11 · 292 mTier B
Section V · Before Botulinum Toxin
Pre-Procedure Washout & Post-Procedure Barrier Support
Injectables usually need no washout beforehand, but keep exfoliating acids, retinoids and spicule products off the injected area for 24–48 hours after.
Compare audited examples: retinoid, exfoliating acid, spicule →After the session · Recovery & photoprotection
- Cicaplast Baume B5+ Soothing Therapeutic CreamLa Roche-Posay · Barrier / Peptide / Hydrator
- Atobarrier 365 CreamAestura · Barrier / Peptide / Hydrator
- Madagascar Centella Hyalu-Cica Water-Fit Sun Serum SPF50+ PA++++SKIN1004 · Photoprotection
Editorial guidance from common clinic practice, not medical advice: your treating doctor's pre- and post-care instructions come first.
Field Notes
Frequently Asked Questions
What skin depth and anatomical layer does Botulinum Toxin target?
Botulinum Toxin (Botulinum Toxin Type A Neuromodulator) targets Intramuscular (Masseter / Frontalis / Corrugator >4.5mm) · Intradermal Micro-Botox (0.8–1.2mm): Papillary Dermis (0.3–1.5mm), SMAS Fibromuscular Layer (Fibromuscular · 4.5mm). Blocks acetylcholine release at the neuromuscular junction — intramuscular for masseter and frown muscles, intradermal micro-dosing for pores and oil.
How painful is Botulinum Toxin, what is the downtime, and what is the evidence-based session interval?
Pain index 3/10. Usually none; ice or topical numbing for micro-Botox. Downtime: 0 hrs · pinpoint bumps for 15–30 minutes. Interval: Every 3–4 months (masseter 4–6 months).
How do I verify an authentic Botulinum Toxin syringe and what is a fair price in Singapore?
HSA-registered brand, lot and expiry on the vial; Dilution volume stated; Units recorded in your notes. Ask to see the brand, lot and expiry on the vial and the dilution volume. Grey-market and counterfeit toxin vials circulate online; Singapore clinics should only use HSA-registered product. Dysport units are not interchangeable with Botox or Xeomin units. Beauty.net's 2026 Singapore benchmark for Botulinum Toxin (50 units (masseter jaw reduction or 3-area upper face)) is a fair range of S$480–S$850 (~S$13/unit median) with a median of S$650, incl. 9% GST.