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Formulation Audit · La Roche-Posay · Triple-Action Azelaic Acid, BHA & Zinc Adult-Blemish & Post-Acne Mark Gel-Cream · $36 USD

Effaclar A.Z. Gel-Crème (Azelaic Acid + Salicylic Acid + Zinc Gluconate + Sodium Hyaluronate)

Holy Grail INCI Ledger ↗ Acquire ($36) ↗ Affiliate link — labelled partner placement
Skin Suitability
Adult acne-prone, combination, oily, and post-inflammatory erythema/hyperpigmentation (PIE/PIH) skin
Chemical Equivalent
The INKEY List 10% Azelaic Acid Serum ($18 — lacks Salicylic Acid, Zinc Gluconate, and Diglycerin)
Molecular Incompatibilities
Avoid layering with another high-strength Azelaic Acid or 2% BHA leave-on exfoliant in the same routine
Creator Hype
88/100
Buyer Efficacy
91/100

Section V · Regimen Clash Check

Will Effaclar A.Z. Gel-Crème (Azelaic Acid + Salicylic Acid + Zinc Gluconate + Sodium Hyaluronate) Clash With Your Routine?

Add the rest of your routine after La Roche-Posay Effaclar A.Z. Gel-Crème (Azelaic Acid + Salicylic Acid + Zinc Gluconate + Sodium Hyaluronate) and run the check — it cross-examines retinoids, acids, vitamin C, spicules and occlusives, privately in your browser.

City
Clinic Preference
Or try a sample routine:

Empirical Buyer Synthesis

What Buyers Actually Report

[r/EuroSkincare] [r/SkincareAddiction]: La Roche-Posay's 2025/2026 flagship adult-acne launch placing Azelaic Acid at #2 INCI alongside Salicylic Acid (#7 INCI), Panthenol (#8 INCI), Zinc Gluconate, Diglycerin, Sodium Hyaluronate, and plant-derived C15-19 Alkane. Targets inflammatory blemishes, clogged pores, and post-inflammatory erythema/hyperpigmentation in one step without silicone pilling.

Verbatim INCI Composition

Full Ingredient List

Aqua/Water/Eau, Azelaic Acid, C15-19 Alkane, Glycerin, Triethyl Citrate, Diglycerin, Salicylic Acid, Panthenol, Silica, Ammonium Polyacryloyldimethyl Taurate, Taraxacum Officinale Rhizome/Root Extract, Dandelion Rhizome/Root Extract, Zinc Gluconate, Glyceryl Stearate, PEG-100 Stearate, Sodium Hyaluronate, Sodium Hydroxide, Sodium Phosphate, Disodium Phosphate, Hydroxyethylcellulose, Hydroxypropyl Starch Phosphate, Tetrasodium Glutamate Diacetate, Citric Acid, Trisodium Ethylenediamine Disuccinate, Pentylene Glycol, Polysorbate 60, Parfum/Fragrance

Source: inkeedecoder.com. Check the pack — formulas change.

Section V · Compare

Compare Against Peer Formulations

Effaclar A.Z. Gel-Crème (Azelaic Acid + Salicylic Acid + Zinc Gluconate + Sodium Hyaluronate) beside the closest formulations in the index — same active family first, then the nearest related one — with a routine-conflict and washout summary.

Compare with 2 peers →

Field Notes

Frequently Asked Questions

Is La Roche-Posay Effaclar A.Z. Gel-Crème (Azelaic Acid + Salicylic Acid + Zinc Gluconate + Sodium Hyaluronate) worth it?

Beauty.net verdict: Holy Grail. Creator hype 88/100 against buyer efficacy 91/100. [r/EuroSkincare] [r/SkincareAddiction]: La Roche-Posay's 2025/2026 flagship adult-acne launch placing Azelaic Acid at #2 INCI alongside Salicylic Acid (#7 INCI), Panthenol (#8 INCI), Zinc Gluconate, Diglycerin, Sodium Hyaluronate, and plant-derived C15-19 Alkane. Targets inflammatory blemishes, clogged pores, and post-inflammatory erythema/hyperpigmentation in one step without silicone pilling. Best for: Adult acne-prone, combination, oily, and post-inflammatory erythema/hyperpigmentation (PIE/PIH) skin.

What should I not mix with La Roche-Posay Effaclar A.Z. Gel-Crème (Azelaic Acid + Salicylic Acid + Zinc Gluconate + Sodium Hyaluronate)?

Avoid layering with another high-strength Azelaic Acid or 2% BHA leave-on exfoliant in the same routine Run your full routine through the Regimen Clash Check to catch other conflicts.

What is a cheaper dupe or chemical equivalent for La Roche-Posay Effaclar A.Z. Gel-Crème (Azelaic Acid + Salicylic Acid + Zinc Gluconate + Sodium Hyaluronate)?

The INKEY List 10% Azelaic Acid Serum ($18 — lacks Salicylic Acid, Zinc Gluconate, and Diglycerin) Compare the INCI lists — a shared hero active matters more than the brand.