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Formulation Audit · Bioderma · Post-Procedure Microbiome & Epidermal Recovery Barrier Balm-Cream · $22 USD

Cicabio Crème+ Ultra-Repairing Soothing Cream (Acetyl Dipeptide-1 Cetyl Ester + Polyglutamic Acid + Squalane)

Holy Grail INCI Ledger ↗ Acquire ($22) ↗ Affiliate link — labelled partner placement
Skin Suitability
Post-procedure (Pico laser, RF microneedling, peels), compromised barrier, dry, sensitive, and retinoid-sensitized skin
Chemical Equivalent
La Roche-Posay Cicaplast Baume B5+ ($18 — uses 5% Panthenol + Madecassoside instead of Bioderma's Acetyl Dipeptide-1 Cetyl Ester + Sodium Polyglutamate + Jojoba/Squalane complex)
Molecular Incompatibilities
None — safe post-procedure and retinoid recovery buffer
Creator Hype
82/100
Buyer Efficacy
92/100

Section V · Regimen Clash Check

Will Cicabio Crème+ Ultra-Repairing Soothing Cream (Acetyl Dipeptide-1 Cetyl Ester + Polyglutamic Acid + Squalane) Clash With Your Routine?

Add the rest of your routine after Bioderma Cicabio Crème+ Ultra-Repairing Soothing Cream (Acetyl Dipeptide-1 Cetyl Ester + Polyglutamic Acid + Squalane) and run the check — it cross-examines retinoids, acids, vitamin C, spicules and occlusives, privately in your browser.

City
Clinic Preference
Or try a sample routine:

Empirical Buyer Synthesis

What Buyers Actually Report

[r/EuroSkincare] [r/tretinoin]: Bioderma's next-generation Cicabio Crème+ replaces the older copper-zinc formula with a biomimetic lipid and dual-humectant matrix (Squalane, Jojoba Seed Oil, Rapeseed/Sunflower Oils, Sodium Polyglutamate, Sodium Hyaluronate, Xylose, and Antalgicine neuro-soothing peptide Acetyl Dipeptide-1 Cetyl Ester). Praised for calming post-laser, post-peel, and retinoid irritation with zero fragrance or alcohol.

Verbatim INCI Composition

Full Ingredient List

Water/Eau, Caprylic/Capric Triglyceride, Glycerin, Polyglyceryl-3 Polyricinoleate, Brassica Campestris (Rapeseed) Seed Oil, Butylene Glycol, Tapioca Starch, Hydrogenated Rapeseed Oil, Xylose, Polyglyceryl-3 Diisostearate, Simmondsia Chinensis (Jojoba) Seed Oil, Magnesium Sulfate, Pentylene Glycol, Squalane, 1,2-Hexanediol, Caprylyl Glycol, Sodium Polyglutamate, Sodium Citrate, Xanthan Gum, Sodium Hyaluronate, Tocopherol, Mannitol, Rhamnose, Xylitol, Acetyl Dipeptide-1 Cetyl Ester, Helianthus Annuus (Sunflower) Seed Oil, Citric Acid, Fructooligosaccharides

Source: inkeedecoder.com. Check the pack — formulas change.

Section V · Compare

Compare Against Peer Formulations

Cicabio Crème+ Ultra-Repairing Soothing Cream (Acetyl Dipeptide-1 Cetyl Ester + Polyglutamic Acid + Squalane) beside the closest formulations in the index — same active family first, then the nearest related one — with a routine-conflict and washout summary.

Compare with 2 peers →

Field Notes

Frequently Asked Questions

Is Bioderma Cicabio Crème+ Ultra-Repairing Soothing Cream (Acetyl Dipeptide-1 Cetyl Ester + Polyglutamic Acid + Squalane) worth it?

Beauty.net verdict: Holy Grail. Creator hype 82/100 against buyer efficacy 92/100. [r/EuroSkincare] [r/tretinoin]: Bioderma's next-generation Cicabio Crème+ replaces the older copper-zinc formula with a biomimetic lipid and dual-humectant matrix (Squalane, Jojoba Seed Oil, Rapeseed/Sunflower Oils, Sodium Polyglutamate, Sodium Hyaluronate, Xylose, and Antalgicine neuro-soothing peptide Acetyl Dipeptide-1 Cetyl Ester). Praised for calming post-laser, post-peel, and retinoid irritation with zero fragrance or alcohol. Best for: Post-procedure (Pico laser, RF microneedling, peels), compromised barrier, dry, sensitive, and retinoid-sensitized skin.

What should I not mix with Bioderma Cicabio Crème+ Ultra-Repairing Soothing Cream (Acetyl Dipeptide-1 Cetyl Ester + Polyglutamic Acid + Squalane)?

None — safe post-procedure and retinoid recovery buffer Run your full routine through the Regimen Clash Check to catch other conflicts.

What is a cheaper dupe or chemical equivalent for Bioderma Cicabio Crème+ Ultra-Repairing Soothing Cream (Acetyl Dipeptide-1 Cetyl Ester + Polyglutamic Acid + Squalane)?

La Roche-Posay Cicaplast Baume B5+ ($18 — uses 5% Panthenol + Madecassoside instead of Bioderma's Acetyl Dipeptide-1 Cetyl Ester + Sodium Polyglutamate + Jojoba/Squalane complex) Compare the INCI lists — a shared hero active matters more than the brand.